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Vismodegib (Brand Name: Erivedge)

What's it used for?

It is used to treat a skin cancer known as basal cell carcinoma. It is used when the skin cancer has spread to other parts of the body or has come back after surgery.

How do I take it?

  • It is often taken in 1 dose a day.
  • You may take it with or without food.
  • Swallow capsules whole. Do not open or break.

What should I know before taking it?

  • Tell your doctor, nurse, and pharmacist the names of all medicines you take. This includes over-the-counter medicines, vitamins, and herbal products.
  • Tell your doctor, nurse, and pharmacist if you have any allergies.
  • Tell your doctor if you are pregnant or plan to become pregnant.
  • Tell your doctor if you are breastfeeding or plan to breastfeed.
  • Tell your doctor if you have any other medical conditions. 
  • Do not donate blood while taking this drug and for 24 months after you stop.

How do I handle it safely?

  • Wash your hands after handling it.
  • Pregnant women should not handle it.

What about sexual activity?

  • Men should wear condoms with spermicide during treatment if partner is of childbearing age. Do not donate sperm.
  • Women of childbearing age should use highly effective birth control during treatment and for 3 months after.

How do I store it?

  • Store at room temperature.
  • Keep away from heat, moisture, and direct light.
  • Keep out of the reach of children or pets.

What are the side effects?

The common ones (more than 3 in 10 people have them)
  • Muscle spasms
  • Hair loss
  • Abnormal taste
  • Weight loss
  • Tiredness (fatigue)
  • Nausea
  • Loss of menstrual cycles (in women)
Other side effects
  • Diarrhea or constipation
  • Decreased appetite
  • Muscle pain 
  • Vomiting
  • Changes in taste

When do I call my doctor?

Call your doctor if you have any of these:

  • Any bothersome side effects or any side effects that do not go away
  • Any signs of an allergic reaction, such as rash, hives, or tightness of chest
  • Menstrual (period) changes

Who do I call with questions?

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What’s this drug’s class?

Antineoplastic agent, hedgehog pathway inhibitor 

8/2017

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